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To quote the Reverend William Paley's Natural Theology, regarding a beautiful instance of adaptation: 'A conformation so happy was not the gift of chance'.
The Nudix superfamily represents a rare instance of adaptation of the β-GF as a scaffold for catalytic activity.
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It remains conceivable that some instances of adaptation can lead to sub-optimization or even global failures.
It is the combination of mutation and the selection filter that produces the extraordinary instances of adaptation we can document in nature.
49, 50 A fraction of the studies have the primary goal of exhibiting instances of adaptation where the footprints of natural selection are detectable at the molecular level of polymorphism and divergence.
A comparative analysis with genomic regions, known to be under positive selection [ 15], revealed that a significant fraction of the TFBS-ID identified by us represent instances of adaptation in human populations.
In a recent study, Arbiza et al. [ 1] found that TFBS are under weaker selection than protein-coding regions of genes although these authors could observe several instances of adaptation in TFBS.
A striking instance of journalistic adaptation to the new language appeared in Elisabeth Bumiller's recent New York Times profile of a key policymaker in the Obama administration, Undersecretary of Defense for Policy Michele Flournoy.
The vast majority of examples of repeated adaptive evolution were morphological (53 %), with instances of repeated adaptation less frequently reported for behavior (22 %) or physiology (18 %), and rarely for life history (7 %; Fig. 1b).
Christopher retains a view of mathematics as dependent on memory and external validation through instances of strategic adaptation and abstraction.
Phenology is an important fitness component, especially for annual plants, and many instances of molecular adaptation have been reported for genes involved in flowering pathways.
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