There has been extensive development and validation of a number of site- and disease-specific modules for the FACT, including, for instance modules for anaemia and fatigue, colorectal, breast and lung cancer.
No matter the direction of the net flux between f9SS and f10SS, for instance, modules 2, 3, and 6, which do not contain the recycling pathway f2SS, always have a higher up-regulated activity of X1 (with an averaged value above 3 fold) than modules 1, 4, 5, and 7 (with averaged values ranging from just above 1 to less than 2 fold).
For instance, module 1, the largest one, is assigned to III.4 Coenzyme transport and metabolism, III.5 Energy production and conversion, III.8 Nucleotide transport and metabolism.
For instance, module I was subdivided two small modules (Qmax = 0.20, Z-score = 7.01) that corresponded to the somatosensory/motor and auditory systems, respectively, which was consistent with previous studies showing that the regions were associated with different functional components or clusters [16], [18], [39].
For instance, module 83 passengers are up-regulated in ER-negative samples and down-regulated in ER-positive samples.
For instance, Module 13 (Fig. 5 right) peaks in S phase, is highly enriched for histones, and is regulated by ESP1 and HSL1, mitosis and budding regulators.
These represent, for instance, the modules or subsystems that could be optimized by "mixing the protocols" to achieve the high level of sophistication that artificial cells requires.
Each axiomatization is modular, with, for instance, separate modules devoted to the relevant geometrical and material properties.
The Halo software package from Indica Labs, for instance, includes modules for counting cells expressing one or two proteins in the nucleus or cytoplasm, counting cells positive for membrane staining, assessing in situ hybridization, and more.
As found in the visual cortex, which is mapped both according to polar and eccentricity topographical mapping, additional axes of topographical mappings may be exposed in the auditory cortex in the future, possibly, for instance, in modules for tuning width or binaural interactions [29], [55].
For instance, new modules can be used to read pathway information from other databases, as was shown for the entire PID [ 65].
