The instance of freemartins in sheep may be increasing in concert with the rise in twinning (freemartins are the result of male-female twin combinations).
Britain's intervention in Libya, for instance, unfolded in concert with the United States, not with its European partners.
Although we regard this as a very preliminary step toward an understanding of the evolution of noncoding functional elements in bacteria, it is clear that promoters in the SD species group are evolving differently in different lineages and different categories of genes and may in some instances be evolving in concert with protein-coding genes of the same biochemical category.
For instance, positive-feedback circuits, in concert with stochastic gene expression, can generate multiple states, such as the gene X-high and X-low populations shown in Fig. 1D, in a reversible manner.
For instance, do these sites work in concert with serine 10 to modulate Puma stability or are they involved, as outlined above, in regulating BH3-only function by controlling binding to anti-apoptotic Bcl2 family proteins.
PKCα/β inhibitor Go6976 blocks the invasion of urinary bladder carcinoma cells [ 25] and PKC antisense oligonucleotide LY900003 is in clinical development as a drug against breast cancer to be used in concert with, for instance, chemotherapy [ 26].
For instance, the largely Hutu FDLR is staging attacks in concert with another armed group called the Nyatura against villages perceived as sympathetic to the Tutsis.
For instance, nutlin-3 has been shown to act in concert with various conventional chemotherapeutics to activate p53, in efforts to improve the treatment efficacy and reduce the collateral damage caused by chemotherapy.
In case of midline tumor, radical vulvectomy in concert with bilateral inguino-femoral lymphadenectomy was performed.
Importantly, the epigenome itself is subject to environmental influences, as documented in multiple instances [ 58- 61], and thus could act in concert with genetic variation to explain phenotypic variation and plasticity [ 62, 63].
