Sentence examples for instability in the development from inspiring English sources
Many of the best-known Irish authors lived and worked for long periods in exile, often in England, and this too has contributed to a sense of instability in the development of a canon defined as uniquely Irish.
The Intra Allerød Cold Period induced instability in the development of the woody communities.
In this study, we investigated the role of genetic instability in the development of HNSCC and in particular in tumour multiplicity phenomena of the upper respiratory tract.
This study analyzed data from the Epidemiology of Diabetes Interventions and Complications (EDIC) study to see whether longer-term follow-up of Diabetes Control and Complications Trial (DCCT) patients reveals a role for glycemic instability in the development of microvascular complications.
Imbalance of the paravertebral muscles could lead to biomechanical instability resulting in the development of a scoliotic curve.
To assess a role of microsatellite instability (MSI) in the development of gastric adenocarcinoma or adenoma from chronic gastritis, we analysed mutations of five microsatellite loci in gastritis, adenoma and adenocarcinoma retrospectively.
This clonal evolution in combination with chromosomal instability may result in the development of variant subclones within one tumour harbouring different sets of genetic changes.
One type of genomic instability usually predominates in the development of a specific CRC, although MSI and CIMP often coexist [ 13].
Given the role of chromosomal instability and aneuploidy in the development and progression of PDA, we hypothesized that STAG2 would be somatically deficient in a subset of PDA patients.
Future studies investigating clonal evolution should clarify, whether haploinsufficiency of both genes may cooperate early in the process of leukemic transformation by disordering key processes of differentiation and proliferation and whether they may also play a critical role in the induction of chromosomal instability finally resulting in the development of clones with complex karyotypes.
Our analysis showed that chromosome instability and LOH, rather than mini- and microsatellite instability, play significant roles in the development of lung cancer.
