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Some levels of the categorical variables were grouped to avoid low numbers in levels that could create instability in data analyses.
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Probabilities were assumed to be constant after the first five years post-diagnosis, to overcome the instability in the data due to the small numbers of people being followed in these years.
Finally, there is possible but unknown instability in the data due to the limited number of days with the Heat Index equal to or above 100 °F during the study period.
The content of S-HBsAg was assayed after soaking, and did not show any instability in tested parameters (data not shown).
Redundancy in data can cause convergence instability of models.
Noise and perturbation in data may cause numerical instability in this method.
It is tempting to conclude a causative role for genetic instability in CRC progression from these data.
Microsatellite instability analysis data was available in 741 samples, and the incidence of MSI-H, microsatellite low and microsatellite stable was 11.2% (83 out of 741), 18.6% (138 out of 741) and 70.2% (520 out of 741), respectively.
This approach enabled not only detection of the macro-instability in measured velocity data but also to quantify its relative magnitude (a ratio of kinetic energy captured by the macro-instability to total kinetic energy of the flow).
Moreover, we did not obtain epigenetic status or microsatellite instability (MSI) data, which plays a role in CRCs.
The chromosomal aberrations and aneuploidy found in mouse cells mutant for Brca1 or Brca2 are in agreement with the pathological data showing chromosomal instability in BRCA-associated breastumoursrs [ 64*].
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CEO of Professional Science Editing for Scientists @ prosciediting.com