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The incidences found were compared to the incidences of MMNs detected by visual inspection of difference waveforms.
The top three components comprising ≥95% of the CD signal were then selected for reconstitution for the final fit plotted in Figure 2. Inspection of difference spectra confirmed that additional components consist of noise.
A detailed inspection of difference electron density maps around the Zn2+ binding pocket allowed modelling of one Zn2+ ion with 50% occupancy for one chain only (chain A).
In rare cases when very high quality single crystal data are obtained, multipole analysis, followed by topological analysis of static electron density (versus inspection of difference maps) can give insights into metal metal bonding, as exemplified by (re)investigation of the archetypal Mn2 CO 10.
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In each method, trial partial structures for heavy or anomalously scattering atoms are often obtained by the inspection of difference-Patterson functions or by semiautomated analysis.
Detailed inspection of differences among genes may provide information about molecular mechanisms of adaptation processes in a new host, and therefore, additional information useful for predicting sequence changes which will occur in the invader virus genome in the near future.
The technique is also not objective, since visual inspection of the difference image is required.
Kauffmann et al. (2009) suggested the inspection of the difference between distributions of signal levels of PM and MM probes as part of the quality assessment of microarray experiments.
Refinements were terminated when there were no significant changes in Rwork and Rfree values and inspection of the difference density maps suggested that no further corrections or additions were justified.
The structure was found to be correct in all aspects and inspection of Fourier difference maps revealed no missing or incorrectly positioned atoms, and no evidence of possible H-atom site disorder, which the previous work had mooted as a possibility.
As parallel trends between the treatment group and the control group in the absence of the treatment is a crucial assumption for difference-in-difference estimates, we devote the next subsection to the inspection of trend differences.
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