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All of them were first checked by the use of trimAl (automated1 mode) (Capella-Gutierrez et al. 2009); subsequently, alignments were visually inspected: Manual editing was only used to correct few misalignments in proximity of small gaps (supplementary fig. S1, Supplementary Material online).
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Software [47]), plotted and carefully inspected for manual and ICA dependent artifact-rejection.
MSAs that did not meet these criteria were manually inspected to evaluate further manual editing (split alignments).
To monitor primary tumor growth, mice were inspected weekly by manual palpation for tumor appearance.
Following FIRST extraction of hippocampal masks, an expert, blind rater (EHA) inspected and made manual adjustments when necessary so each mask conformed to established rules and boundaries [ 32].
Typically, in manual inspection, the inspected surface is about 0.05% of the total steel surface produced.
All surface models in our study were visually inspected for accuracy and manual corrections were performed in the event of tissue misclassification/white matter errors while blinded to diagnostic group information.
One alternative approach is to use camera-based vision system to pre-record a video of the roundabout traffic at time of interest, such as peak hours, and then traffic engineers manual inspect the video to collect accepted/rejected gap size [14].
In our experience, it takes on average at least a day to manual inspect and collect a few hundred samples of gap sizes for a 3-hour video (the exact time needed depends on the number of samples of accepted/rejected gap sizes in the video).
Finally, in order to manual inspect the results obtained by the software, files containing the single-base coverage on each chromosome and/or scaffold of the genome are generated.
We visually inspected the alignments and performed manual refinement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com