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During the process we keep track of the inliers rate within the set C ab, as well as the time required by each technique to determine their best correspondence triplet within C ab. Once the alignments are terminated, we visually inspect the alignment outcome and count the number of errors for each technique, reported in Table 1.
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The authors need to carefully inspect the alignments to detect obscure sequences.
We carefully inspected the alignment to verify its consistency with the literature.
In the remaining cases both alleles were observed by inspecting the alignment manually, but Maq failed to call both of the SNP alleles.
The leader sequences, framework regions, complementarity determining regions (CDRs) and J-regions were identified by inspecting the alignment of the F1-40 heand and light chains to other antibody sequences [26] [30].
The disrupted RM genes were reconfirmed by manually inspecting the alignment of the remaining parts.
We also manually inspected the alignment (Additional file 1: Figure S1) using IGV [ 19, 20].
Inspecting the alignment estimate from the MAP point using a "gold" plot demonstrates alignment uncertainty (data not shown).
The 3' and 5' splice sites were identified manually by inspecting the alignment and confirmed by comparing the genomic sequences to the corresponding exon sequences.
Inspecting the alignment of the 193 TvBspA with TMD-CCT identified several related sequences (co-aligned) based on shared CT sequences.
We visually inspected the alignment to verify that key sequence motifs (e.g., HRD and DGF motifs) and core hydrophobic residues are aligned correctly.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com