Exact(4)
CUAs have recently been conducted in the field of insomnia research [ 7, 37- 41].
Although sleep diaries represent a core assessment component in insomnia research [ 48], patients with insomnia generally over-estimate wake-time [ 49].
Several tools for measuring insomnia have been developed [ 6- 9] reflecting the growing interest and need for assessment instruments in insomnia research.
If the Krystal et al (2003) trial had used the WASO >30 minute criteria, which is standard for insomnia research, then approximately 40% of participants would have been excluded from the original study.
Similar(56)
While there is inconclusive evidence that sleep hygiene alone is effective as a treatment for insomnia, some research studies have shown improvement in insomnia for patients who receive sleep hygiene education in combination with cognitive behavioral therapy practices.
We also had a comparably large number of participants in each treatment group, and included measures of day-time functioning, which have not been adequately studied in earlier insomnia treatment research.
The CAR has been investigated in a range of clinical populations including the assessment of daytime dysfunction in insomnia; however little research, if any, has specifically examined its relation to sleep architecture, or night-time difficulties associated with insomnia.
The Cochrane Report, a meta-analysis of major music studies, reported last year that while there is some evidence to suggest that music may help treat insomnia, "more high-quality research is needed".
This wide range in prevalence stems in most part from the many definitions of insomnia used in previous research.
The PSQI is now one of the most commonly used assessments for the evaluation of insomnia severity in sleep research [ 65, 66], and its validity has been demonstrated for patients with mental disorders [ 62, 67], for patients with different somatic diseases [ 68], and for healthy elderly subjects [ 63].
"It is a significant change in the landscape of what we can ask of a medicine in treatment of this disease," said Andrew D. Krystal, director for the sleep research laboratory and insomnia program at Duke University and the lead investigator in the trial, as well as a consultant to Sepracor.
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