A woman in Boston blamed herself for insisting, in spite of a financial hardship, that her husband fly to the West Coast for his stepdaughter's wedding.
Favreau insisted that in spite of the economic forces that now constrain film-makers such as himself, they're determined to combine commercial triumph with creative achievement.
Your historic streak has been snapped by me," Colbert insisted, but, in spite of the goading, Stewart refused to be angry about the loss.
The volunteers and would-be volunteers I spoke to insisted that, in spite of their precarious situations, they had been 'empowered' and were 'moving ahead'.
They were, Ekirch insists, fun: "In spite of myriad perils, it was night, not morning, not afternoon, that was valued most".
ON THE face of it, the failure of John McDonnell is reassuring to those who insist that, in spite of the imminent departure of Tony Blair, there will be no retreat from New Labour's centrist ways.
So proponents of an intrinsic unnaturalness argument can insist that in spite of not being able to provide principled grounds for distinguishing between the two kinds of cases, they still know that creating chimeras is wrong.
It was this refuse heap, in one of the most evocative scenes in the novel, that Umar insisted on visiting, in spite of the attempts by the Christian Patriarch Sophronius, who stayed behind in the city after his commander fled, to dissuade him.
His life was saved by a tank driver's helmet the organisers insisted he wear, in spite of which he suffered a severe concussion and was in a coma for several days.
Since birth of the first "test tube" baby Louise Brown in 1978, pioneered by physiologist Robert G. Edwards and surgeon Patrick C. Steptoe, there was a great advance in reproductive biomedicine made by amazing people, who insisted on this path in spite of pressure from society.
