Exact(6)
Interrogation of databases including the preliminary releases of sequences from the non-Ixodes hard tick R. appendiculatus, B. microplus, A. americanum and A. variegatum genome projects yielded no or only insignificant hits.
Simrank reported fewer of these insignificant hits than BLAST but megaBLAST and SSAHA2 ignored them all.
The shuffled (synthetic) DNA library was included in the dataset as a negative control where only insignificant hits are expected.
To avoid insignificant hits, only subsequences with scores that exceed the score threshold Tseed are hashed as subsequences for seed.
We applied two cutoff levels to avoid inclusion of insignificant hits: a score cutoff of 50 bits, and an overlap cutoff of 50%, as applied in Inparanoid [ 40].
This ratio is multiplied by 1 − E (h i ) to factor in the significance of the hit, so that insignificant hits will deteriorate the score.
Similar(54)
Assuming long-distance companies pass on all the increases to their customers, and the Bells increase rates by 30percentt, consumers in Texas would pay from $4.84 to $7.68 more a line per month, a not insignificant hit.
However, using AvrB as a sequence query with the sensitive profile-based homology detection method COMPASS [22], [23] identified an insignificant hit (E-value 5) to the fic domain structure (3cuc).
We did not use any regions with overlapping Pfam domains for the evaluation and also completely excluded regions with insignificant domain hits, i.e. hits below gathering threshold.
Presumably, the latter plot should represent the background distribution of insignificant BLAST hits.
RpoD exhibits only insignificant BlastP hits to acholeplasmas' sigma factors (minimal e-value 9e-08, score 47), and no ortholog was predicted via PanOCT.
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