We also tested NESP55 expression under anaerobic conditions in the human medulloblastoma cell line D324 Med and in the human supratentorial PNET cell line PFSK1 indicating insignificant (1.2-fold; standard error of mean.035) or minor (2.4-fold; standard error of mean.178; p<.001) induction, respectively.
Here we show that this gene, nitA, is expressed more or less uniformly in somatic cells and gonidia (there is only an insignificant, 1.36-fold higher expression in somatic cells).
Resistin also elevated both the mRNA level (17- and 4-fold) and protein secretion (1.6- and 2.3-fold) of IL6 and IL8, while only a small (2.6-fold) and insignificant stimulatory effect was seen on the TNF gene (Figure 1A, left).
The contributions of specific residues to the delicate balance between function, stability and folding rates could be determined, in part comparing the sequences of structures having identical folds, but insignificant sequence homology.
Changes in levels of the other Claudins did not follow a discernable pattern and were either minimal (≤1.5 fold change) or insignificant (p≥0.05) (Figs S4 and S5).
pERK induction ranged from statistically insignificant to more than 600-fold in CAMA-1 cells exposed to HRG.
Genes with an expression ratio between 0.5- and 2-fold were deemed biologically insignificant and were filtered out.
In an addition, genes which were selected between 0.5- and 2-fold were deemed biologically insignificant and were filtered out.
Weak regulation signals can easily be overlooked in a single dataset, i.e. the genes will likely receive an insignificant p-value due to their low fold changes compared to a relatively high variance.
The gray substance in some of the inner pleat folds is a kind of insignificant mildew, less toxic than what is found on some foreign cheeses.
