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Recent large therapeutic trials on antibodies have shown that these drugs, when applied to large populations, show generally insignificant efficacy but with encouraging results in well identified subpopulations, especially in the early stages of disease [ 10].
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With the presence of the outlier study, only insignificant overall efficacy of alendronate could be observed with substantial heterogeneities.
The (statistically insignificant) reduction in efficacy of our hand-rolled beads is presumably due to a less favorable area-to-volume ratio, as the hand-rolled beads were larger than the commercially available beads.
One-way sensitivity analysis revealed that the most sensitive variables were probability of developing a DVT resulting from the insignificant difference in treatment efficacy.
While statistically insignificant, ZB497 showed a slightly greater degree of efficacy than tamoxifen and 4-OHT treatments.
As seen in the figure, the efficacy of the optical phonon scatterings is insignificant at low gate voltage compared to those of the acoustic ones.
However, once students' precourse knowledge and self-efficacy were account for, these differences became insignificant.
Based on the results, it was established that there is an insignificant negative correlation between gender and career indecision, however, between self-efficacy on making career decisions and gender of participants there is a significant positive correlation.
Not to our surprise, participants' self-efficacy both for English and for mobile devices also yielded insignificant results (see Tables 7 and 8).
CH4987655 exhibits slow dissociation from the MEK enzyme, remarkable in vivo antitumor efficacy both in mono- and combination therapy, desirable metabolic stability, and insignificant MEK inhibition in mouse brain, implying few CNS-related side effects in human.
Regarding GMA as a therapeutic intervention in patients with UC, it is of paramount importance to know that clinical efficacy outcome reports vary from an 85% [ 25, 27, 28] to a statistically insignificant level [ 29].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com