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CBZ does not have any preference of sorption sites on GP as suggested by Langmuir-type sorption and insignificant change of SMX sorption nonlinearity and SMX release ratio after CBZ addition.
Regarding total urea and creatinine levels, an insignificant change of total urea and creatinine levels in normal treated rats with D. anethifolia total extract as compared to normal control group (Table 6) was observed.
It is interesting to note that the insignificant change of uterine weight in raloxifene-treated ovariectomized rats seen in our study confirms the fact that raloxifene lacks uterotrophic activity due to its anti-estrogenic properties in the uterus [ 18].
The significant increase in mean MCV value and insignificant change of mean MCH and MCHC indicate the macrocytic normochromic type of anaemia in infected groups, in agreement with Nadia et al. [ 43] and Gardiner [ 5].
Cadaverine (two positive charges at pH 7.0, channel in open state, o-main, Additional file 3: Figure S4A) and ornithine (one positive charge, channel in open state, o-full, Additional file 3: Figure S4B) did not produce a comparable effect on gating or open probability and only an insignificant change of the overall current (less than 5%).
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Similarly, changing the orders of reads resulted in insignificant changes of the Jaccard index (<0.01).
Analyzing the results, the overeruption percentages between T1 and T2 ranged between 0.5 1.0 % and 1.1 1.2 % in the retention and nonretention mandibular second molars, which are translated into clinically insignificant changes of a tenth of millimetre.
The insignificant changes of total Tau in the soluble fraction in vivo may be attributed to the low percentage of pTau in the total Tau pool.
Both surgical management and hearing aid provision groups gave statistically significant increases in HRQoL of, respectively, 0.084 and 0.038, whereas the other four types gave insignificant changes of therapy (0.017), reassurance (0.008), medical treatment (0.004), and refer on (−0.008).
By contrast, administration of tacrolimus in UN rats induced only mild but statistically insignificant changes of spermatogenesis without effects on body weight gain and testicular development or evidence of testicular injury, although the testosterone level was reduced along with elevated LH level.
Although the use of the EuroQoL for manual therapy for neck pain [ 27] resulted in a statistically insignificant change in quality of life, two other studies demonstrated small, but statistically significant differences in quality of life using the SF-6D for acupuncture for chronic headache [ 35], and using the EuroQoL for spa therapy for ankylosing spondylitis [ 51].
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