Insignificant abnormalities were found in 33 patients: paranasal sinus thickening (13), septum pellucidum cyst (2), pineal cyst (3), arachnoid cyst (3), circle of Willis variants (6), signs of chronic cerebral ischemia (5), doubtful small subependymoma (1).
The reporting radiologist may not know enough to identify or recognise the relevant finding (or to correctly dismiss insignificant abnormalities).
Additional inclusion criteria included clinical laboratory test results within normal limits or with clinically insignificant abnormalities, negative illicit drug and alcohol screening tests, and if appropriate, negative urine pregnancy test, documented bilateral oophorectomy and/or hysterectomy, or postmenopausal status with cessation of menstruation for >2 years.
Thirty-eight candidate variables collected at baseline, consisting of demographics, clinical measurements, medical history, investigator reported ECG (normal, clinically insignificant abnormality or clinically significant abnormality) and laboratory results, were included (listed in table 1).
Morphological abnormalities of their ear vesicles during the embryonic and baby stages were noted.
The film portrayed the abnormalities of normal family life.
The highest number of AEs was in period 5 (800 mg bid) and the fewest in period 4 (600 mg bid); gastric AEs, including transient nausea, flatulence, and loose stools, were more prevalent at 800 mg bid, clinically insignificant biochemical abnormalities at 400 mg bid, and cardiac AEs (transient palpitations) while taking 200 mg bid of ATI-2042.
This CSF abnormality is comparable to CSF abnormality of ADEM.
"Collecting insignificant pieces of matter".
"You ink-dependent, insignificant bit of shaped metal and wood!
