These new insights highlight the complex mechanisms underlying immune dysfunction in septic patients and could promote future therapeutic approaches.
Her unflinching outsider insights highlight everyone's foibles, especially her own.
More recent insights highlight the significance of Hedgehog signalling (Dierks et al, 2008; Zhao et al, 2009).
The previous mechanistic insights highlight the need for lipid/lipoprotein targets that better reflect the burden of atherogenic dyslipidaemia.
We were able to demonstrate that integrating information about pathways can provide additional molecular insights, highlighting a few key genes and pathways.
These insights highlight the significance of mastery experience, vicarious experience, verbal persuasion and affective states as sources of information that can influence parents' perceptions of self-efficacy.
These insights highlight the significance of two key aspects of MDT-parent interactions and the way they contribute to the process of accomplishing common ground within MDTs and between professionals and parents.
11 Similar to traditional systematic reviews, this process can generate new insights, highlight gaps in our knowledge and identify areas of data saturation where no further primary research is required.
These studies have provided several biological insights, highlighting the role of the complement genes in age-related macular degeneration (21– 23), of autophagy in Crohn's disease (24– 26) or of specific regulatory proteins in blood lipid levels (6), among others.
TKI258 binds more tightly to the FGFR1 KD V561M (Ki ~ 35 nM) while binding of PD173074 (Ki ~ 1580 nM) is greatly obstructed (Supplemental Table S1); structural insights highlight the underpinning differences (Fig. 2C).
New insights highlight the interaction between the inflammatory and coagulant response, particularly after surgery, and this association is underlined by randomised trials that show that recombinant activated protein C APCC) significantly reduces sepsis-induced mortality in surgical patients (Bernard et al, 2001; Vincent et al, 2005).
