In conclusion, even a strict endosymbiont-dominated insiders' view needs to incorporate the premises of the outsider's hypothesis (i.e., the outside-to-inside trajectory and host-control over organellogenesis) in order to interpret the current state of organelle topogenesis.
Because host-encoded proteins need progressively to gain access to the endosymbiont, it is reasonable to suggest that the proposed endosymbiont-guided tinkering process unfolded in an outside-to-inside trajectory.
However we feel that traditional models collectively fail to recognize a directional outside-to-inside trajectory for the establishment of molecular factors in the endosymbiont and that the genetic integration of the organelle functions in the host chromosomes follows this pattern.
Such an outside-to-inside evolutionary trajectory seems to us to be inherently appealing because one cannot easily imagine a selective pressure that would result in the establishment in the nucleus of a gene encoding a protein that operated in the IM of the organelle (e.g., a solute carrier) if host-encoded proteins could not first efficiently cross the OM of the endosymbiont.
This involved the simulation of predicted model inside a trajectory box filled with 6940 molecules of solvent (including NaCl and water) and 467 Lipaminoacido acid residues at the temperatures of 0°C, 5°C, 25°C, 37°C, 50°C, and 100°C.
Fig. 2 The red lines along the side represent the small-spaced point charges while the curves inside are the trajectories of different masses.
This systematic bias, in the direction of the force field, shifts the generated trajectories "inside" the nominal Lissajous shape in the rightward part which is run clockwise, and "outside" the shape, in the leftward path which is run counter-clockwise.
Although his work obviously focuses on manipulating the light in the building, it also aims to stay completely open to the visitors' interpretation, depending on their trajectory inside the multicolored maze, the position of the sun and the time of the day.
Sergey Brin was equally clear about Wave's trajectory inside Google.
Open image in new window Fig. 13 Particle trajectory inside the WRH-TWT.
Indoor-to-outdoor (and resp. outdoor-to-indoor) rays are assumed to propagate along a straight horizontal trajectory inside the floor that contains the base-station (resp. user).
