This is the first week in the 40-year history of the ATP rankings when not a single American man is ranked inside the top 20.
Jakupovic was banned in 2015 and was never ranked inside the world's top 300.
The United States is a country of 300 million people and is ranked inside the top 20.
That includes the 21-year-old Ryan Harrison at No. 104, who was ranked inside the top 50 a year ago.
Kanepi, who has struggled with injuries throughout her career, was ranked inside the top 20 as recently as July.
She is 21-8 this year, losing only to players ranked inside the current Top 10, sans her loss to Kim Clijsters in the fourth round of the Australian Open.
The opponent was 75th-ranked Alexandra Cadantu, a 22-year-old who is one of six Romanian women currently ranked inside the top 100.
While each of the American opponents in 2012 featured a top-five player, there is only one Brazilian currently ranked inside the top 100: No. 41 Thomaz Bellucci.
The only thing they all seem to have in common is that none has ever been ranked inside the top ten.
In today's world rankings Federer will retake the No 3 position taken from him last month by Andy Murray and thus end the year ranked inside the top three for the ninth season in succession.
