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These differences between the Transwell inserts influence the translocation rate (Cartwright et al. 2012; Geys et al. 2006).
It appears that the cbh gene inserts influence the plasmid copy number significantly, but the mechanism by which this occurs remains unknown.
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Interestingly, this expression pattern overlaps with that of humans and primates, suggesting that differential genomic elements within the non-coding regions of the BAC insert influenced the expression of the receptor, in a species-specific manner.
Then, our only remaining lack of knowledge concerns what will happen if the transgenic inserts somehow influence each other.
This suggests that these inserts could influence the channels properties by altering the conformational changes associated with calcium transport, and/or cope with specific requirements associated with intracellular calcium homeostasis in the human erythrocyte or hepatocyte host cell.
Thus, differences in the chromatin conformation of the loci into which the transgenes have been inserted likely influence the frequency and not the extent to which the pCAGGS promoter is subjected to methylation, underlying the observed differences in silencing.
The early study by Nolan and Parkes (1973) investigated whether previous experience with the hole-board apparatus with a solid floor inserted would influence frequency of head-dipping on second exposure to the apparatus.
The pore size of the permeable membrane of the inserts also influences the translocation rate of nanoparticles: the larger the pore size, the higher the translocation rate (Geys et al. 2006).
Hovering with a tampon inserted can influence your pee stream, which may spray or become multiple streams.
In addition, other factors related to insert sequence may further influence insert stability.
The principal hypothesis was that insert design influences global sagittal laxity.
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