Sentence examples for insertion factors from inspiring English sources

The biogenesis of Escherichia coli inner membrane proteins (IMPs) is assisted by targeting and insertion factors such as the signal recognition particle (SRP), the Sec-translocon and YidC with translocation of (large) periplasmic domains energized by SecA and the proton motive force (pmf).

The observation that mutation or deletion of genes encoding membrane and membrane-associated components of the SPB can be suppressed by elimination of Ndc1 binding partners at the NPC such as Pom152 or Pom34 has led to the idea that the SPB and NPC may compete for Ndc1 or other NE insertion factors (Chial et al. 1998; Sezen et al. 2009; Witkin et al. 2010; Casey et al. 2012).

Here, we present bioinformatic evidence that the tail-anchored protein insertion factor WRB/Get1, the "endoplasmic reticulum (ER) membrane complex" subunit EMC3, and TMCO1 are ER-resident homologs of the Oxa1/Alb3/YidC family.

Future studies will be required to elucidate the bypass mechanism, but our FRET, together with recent super-resolution imaging data (Burns et al. 2015), lends evidence to the idea that Nbp1 is a key SPB insertion factor.

We hypothesized that if pom152 ∆ suppresses the requirement for Mps3 by liberating a SPB insertion factor, it would likely suppress only the SPB function of Mps3, and pom152 ∆ mps3 ∆ cells would be defective in other Mps3-dependent processes, similar to mps3 ∆75–150 or mps3 ∆2–64 mutants.

Number of RRT catheters, insertion sites, factors potentially associated with the choice of insertion site, duration of catheter use, reason for catheter replacement, and complications were prospectively collected.

Of catheter insertion process factors listed, 170 (75.6%) were able to identify inflation of the balloon while it is still in the urethra.

For the generation of human iPSCs without viral vectors or genomic insertions, pluripotent factors Oct4 and Nanog were cloned in episomal vectors and transfected into human fetal neural progenitor cells.

The PPIs we examined harbor known and putative GBS virulence factors, insertion sequences, transposons, and genes of unknown function.

However, these earlier approaches involved random insertion of reprogramming factors into the cellular genome, with consequent risk of oncogenic transformation.

For instance, nucleotide changes may result in a loss or insertion of transcriptional factors that regulate the transcription of the of HR-HPV genes [ 62].