The uncertainty in timing of returns in remanufacturing is modeled as new job inserting constraint in FJSP.
Linear programming (LP) is used to insert the constraints in the design phase while imposing positivity in closed-loop.
We have then to insert a constraint ψ wz,k,n, wz,k,d ) in order to avoid the trivial solution: (wz,k,n = 0, wz,k,d = 0).
If the insert-size constraint is met, S1 and S2 are reported as paired.
Read pairs that do not map within the correct insert size constraint, map to different chromosomes or are in the wrong orientation, are ignored.
First, the researcher must choose a technology and insert-size constraint, where (1) The choice of a specific read-length is somewhat less important, but the reads must be long and accurate enough to map unambiguously.
In this step, we used the -E option to minimize the noise resulting from pairwise read alignments, and the -A option to use regardless of insert size constraint and/or orientation within pairs.
For any aligned read pair, we can first compare their mapping distance on the genome (calculated from the positions of the best alignments of the two reads) to the insert-size constraint.
A Fog system should secure itself by authenticating user identity, check for data consistency and integrity, service availability, ability to revoke any connection and anonymous key management as well as enhance the protection of connected systems by monitoring and inserting real-time constraints [137 ].
This is another advantage of EBSeq, as the researcher can insert biologically relevant constraints on expression patterns a priori, retaining only those patterns that are specific to the conditions of interest for that particular study (fig. 4 B).
