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Briefly, GDDA modifies the original target sequence by inserting a proportion of the domain sequence (10 50%) ("seed") at every amino acid position of the target sequence.
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They represent a proportion of the UK.
Only 15 of the sequenced clones contained two inserts and 1 clone contained three inserts (a low proportion of 4.3% of concatemer clones).
Further, inserting a randomly selected fill-in value is also inadvisable, unless the proportion of missing data is less than about 30%.
These larger inserts represent a small proportion of the chromosome they are inserted in: 0.2 and 0.3% of the total genome size in E. coli and B. subitlis, respectively.
This insert contains a high proportion of Ser/Thr residues that are targets for autophosphorylation.
Long insert libraries often contain a significant proportion of short insert fragments (corresponding to paired-end reads).
A polymorphic site contains variant nucleotides in a small proportion of sequences, and a gap was inserted at the corresponding position in the remaining sequences.
It is possible that some types of genes have a high proportion of suppressed inserts, and an obvious candidate would be testis-specific genes, which feature low insertion density.
Most individual element copies are evolutionarily young; however, a small proportion of inserts appear to have persisted for longer in the genome.
The insert size distribution of the non-MP oriented FF/RR and FR reads does not show the expected normal distribution, but is more similar to a log-normal distribution with a large proportion of reads from short insert size fragments of <1000 bp.
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