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We designed polyglutamines with a few lysines inserted to overcome the hindrance of extreme insolubility and two D-lysines to limit the lengths of β-strands.
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An emerging approach to overcome this challenge is to insert peptides into a scaffold of high stability, i.e., molecular grafting.
To overcome that limitation, Zhuang's team inserted a cylindrical lens in the microscope's optical path.
Inserting constraints in the smoothing of f allows us to overcome the traditional error-driven approximation of f, which does not provide constraints on the preserved topological features.
To overcome this limitation, investigators can now insert highly avid T-cell receptors (TCR) into T cells that can recognize tumor antigens.
The nasal inserts were displaying porous structure and good bioadhesive strength to overcome the nasal mucociliary clearance.
To overcome uneven heating, a heating gasbag with small holes is inserted into the liner of the vessel to provide heating.
However, there is a need for alternative, site-specific approaches to overcome limitations of random integration (and associated position-effects) and potential instability of inserted transgenes.
To overcome these limitations and facilitate the study of endogenous PC-1, we have inserted HA- or Myc-tag sequences into the Pkd1 locus by homologous recombination.
The in vitro and in vivo characteristics of a nasal insert formulation prepared by lyophilisation of a viscous HPMC gel solution designed to overcome this problem were studied.
To overcome the drawbacks of using a plasmid to express LysE, Ptac, a strong promoter, was inserted in the upstream region of lysE on the chromosome.
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Justyna Jupowicz-Kozak
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