Sentence examples for insensitive activation from inspiring English sources

Microfuel cell systems require microvalves that are chemically tolerant of hydrogen, have thermally insensitive activation mechanisms, and tight geometric constraints.

One-electron and two-electron oxidoreductases typically catalyze oxygen-sensitive and oxygen-insensitive activation of bioreductive prodrugs, respectively.

As discussed above, the network may be modified to ensure that the superset is a steady state, to preserve the original limit cycle's time-insensitive activation levels.

The inability of Jag1 to activate Notch1 in CD4+ T cells but to activate Notch2 signaling in a reporter line (Figure 1B) would be consistent with Lfng activity rendering their Notch1 receptor insensitive to activation by Jag1.

This would not imply that other regions are insensitive to activation of ERs by other factors.

Cytosolic Erk1/2 was insensitive to activation (Fig. 6).

The TM I interface is insensitive to activation state (Fig 3A) and presumably symmetrical.

Thus in the absence of sufficient levels of amino acids, the incorrect positioning of mTorc1 renders it insensitive to activation by growth factors [ 26].

Binding experiments with the SdKefQCTD Q419K mutant, which has previously been shown to be insensitive to activation by GS-X, indicated that this mutant is unable to bind the GSH moiety of DNGSH.

It appears to be relatively insensitive to activation by growth factor receptor tyrosine kinase signaling but important downstream of certain GPCRs, including those for lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), making p110β the only GPCR-regulated type I PI3K isoform outside the hematopoietic system (Ciraolo et al., 2008; Guillermet-Guibert et al., 2008; Jia et al., 2008).

Omalizumab, which has been conceptualized for treating IgE mediated allergic diseases and approved for treating patients with severe persistent allergic asthma in many countries, can neutralize IgE, impede the IgE allergic pathway, and render mast cells and basophils insensitive to activation through IgE/Fc εRI.