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In this paper open-loop (uncorrelated and rotated) random signals are compared against inputs generated in closed-loop operation, with the aim of finding the most appropriate ones to be used in multivariable subspace identification of ill-conditioned processes.

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The RMT determination of FDI was used for a proper modulation of stimulus intensities in the following stimulus response experiments of the DM, because the muscle responses to corticospinal inputs generated by TMS in proximal muscles are generally more difficult to elicit than in distal muscles [17].

Input data from those procedures were generated in-silico by introducing two virtual dimeric enzymes with defined, complex deactivation mechanisms.

Swallowing is modulated by the nervous inputs generated from sensory receptors in the oral, pharyngeal and laryngeal regions via trigeminal, glossopharyngeal and vagus nerves [ 111].

Thirst and vasopressin release are also stimulated by afferent inputs generated though a decrease in effective blood volume perceived by high- and low-pressure receptors and ascending through the IX and X nerves.

LOHA was generated in-house and used a multiple alignment of sequences as its input.

In the first stage, 400 code runs were generated with inputs generated using the LP-Tau algorithm in GEM-SA.

To ensure that the Southampton model was fully compatible, we confirmed that use of Forrest inputs generated the same number of deaths in our model.

We estimated divergence times in the software BEAST [ 61], with input files generated in the BEAST module BEAUti (Additional file 6: Table S4, Additional file 7: Table S5).

We also evaluated species trees against this concatenated gene tree with the same parameters using the *BEAST option in BEAST v.1.7.4 [ 48] including input files generated in BEAUTi v.1.7.4 [ 48].

Using this imaging approach in combination with CRISPR/Cas9 editing and optogenetics, we interrogate neuromodulatory mechanisms of defined populations of neurons in an intact mesolimbic reward circuit and describe how individual inputs generate discrete second-messenger signatures in a cell- and receptor-specific fashion.

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