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Statistically significant genes were used as inputs for gene set enrichment analysis based on GO annotations.
To identify putative homeologous copies on the A, B, and D wheat subgenomes, the highest matching sequence contigs were used as inputs for gene predictions using FGENESH (http://www.softberry.com/) using the ' Triticum aestivum' model.
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Rice orthologs of switchgrass genes were input for Gene ontology analysis using agriGO (http://bioinfo.cau.edu.cn/agriGO/)[ 42] and REVIGO (http://revigo.irb.hr/) [ 84] software.
To effectively apply GPMiner, four gene names were input for gene group analysis by GPMiner to detect co-occurring TFBSs.
The data is publically available (Gene Expression Omnibus Accession# GSE12623, GSE20117 and GSE20118) and was used as input for gene expression QTL analysis.
The list of official symbols of these genes was used as input for gene annotation analysis using DAVID Bioinformatics Resources 6.7 [ 64, 65].
The GC-RMA microarray data processing algorithm was used to generate the primary gene expression data input for gene network construction.
The genes that belonged to informative clusters were then used as the input for gene network analysis using a Bayesian network and nonparametric regression method.
The results of the GWASMA on PC1 were used as input for gene-based association analyses using VEGAS v0.8.27 (http://gump.qimr.edu.au/VEGAS/; Liu et al. 2010).
By enumerating all possible inputs for every gene, we are able to explicitly assess which regulators or combinations of regulators are most important for explaining each gene's observed expression.
More generally, designing functional alternative inputs for every gene of interest will be a challenge.
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