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; Input specificity Once induced, LTP at one synapse does not spread to other synapses; rather LTP is input specific.
Thus only the synapse receiving LTP-inducing stimuli is potentiated, demonstrating LTP's input specificity.
However, the input specificity of LTP may be incomplete at short distances.
NMDA receptor-dependent LTP exhibits several properties, including input specificity, associativity, cooperativity, and persistence.
It thus became necessary to explain how protein synthesis could occur in the cell body without compromising LTP's input specificity.
One model to explain the input specificity of LTP was presented by Frey and Morris in 1997 and is called the synaptic tagging and capture hypothesis.
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Hypothesis testing resulted in a p-value above 0.05 for the entire range of input specificities on all three time scales, indicating that there was no evidence to suggest that the specificity was non-constant on any time scale (figure 2).
We argue that fungal composition patterns reflected multiple roles of fungi in dryland ecosystems, namely: responses of saprotrophic fungi to tree organic matter inputs; specificity of ectomycorrhizal fungi to tree rooting zones; and fungal involvement in biological soil crusts that variably covered non-canopy soils.
Studies of LTP in the marine snail Aplysia californica have implicated synaptic tagging as a mechanism for the input-specificity of LTP.
The suppressive effect of capsaicin was not age-dependent and did not show input-specificity.
This report also showed input-specificity for the baseline capacity for LTD at the PPN Glu-DA synapses and local Glu-DA synapses, indicating distinct roles played in each synaptic pathway.
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