Sentence examples for innovative target for from inspiring English sources

β-Arrestin 2 is an essential negative regulator of sepsis-induced inflammation via TLR signaling and may represent an innovative target for antisepsis drugs.

Because AOX does not exist in hosts, this enzyme has been proposed as an innovative target for antitrypanosomatid drug development, and related attempts have been reported in the literature [ 148].

All these data suggest that β-arrestin 2 is an essential negative regulator of sepsis-induced inflammation via TLR signaling and may represent an innovative target for antisepsis drugs.

Carbonic anhydrase (hCA) IX and XII isoforms are over-expressed both in primary and in metastatic cell lines of hypoxic tumors and are innovative targets for cancer diagnosis and treatment.

As HER2 direct therapy in HER2 positive subtype, new innovative targets for TNBC need to be developed.

We aim to provide a more theoretical basis of oxidative stress-induced autophagy, and provide innovative targets for therapeutic intervention in retinopathy.

Dr. Richman, Vice President, Research and Development-Translational Sciences, explained the role of CTM in drug discovery and development with a special statement on Developing Innovative Targeted Therapies for China.

PEA3 emerges as a potential innovative target upstream from Notch activity for triple-negative cancer and possibly other breast cancer subtypes where PEA3 and/or Notch activities are critical for growth and aggressive phenotypes.

These interesting findings not only provide new insights into the mechanism underlying GRN mutations associated FTLD-TDP, but also present PGRN as a potential, innovative, therapeutic target for treating patients with GRN mutations linked to a number of neurological degenerative diseases, especially FTLD-TDP.

Besides pathophysiological insights, knowledge, translated from a rare disease to a more common health problem, can also include innovative targets or options for treatment.

This construct, which strongly activated CD8+ T cells, was tested as a potential innovative target-specific immunogen for HBV vaccine design [ 118].