Disruption of the blood-labyrinth barrier is closely associated with the pathogenesis of a number of hearing disorders, such as autoimmune inner ear disease, Meniere's disease, meningitis-associated labyrinthitis and genetic diseases [3], [4], [5], [6].
Immune-mediated inner ear disease (IMIED), including local inflammatory diseases of the inner ear and autoimmune inner ear disease (AIED), often leads to inner ear tissue damage and physiological dysfunction.
Corticosteroid treatments are now a common therapy for many forms of hearing loss, such as autoimmune inner ear disease, sudden hearing loss, and Menière's Disease [ 109].
Immune-mediated inner ear disease (IMIED) is one of the few reversible forms of sensorineural hearing loss.
VNG is a technology that can test whether dizziness is caused by inner ear disease; it uses an infrared camera to track the pupil in the dark.
Health care professionals tending to patients with inner ear disease face inquiries about therapy options, including treatments that are being developed for future use but not yet available.
To utilize the rapidly accumulating genetic information for developing new therapeutic technologies for inner ear disease, it is necessary to design technologies for expressing transgenes in the inner ear, especially in the organ of Corti.
Phillips et al. [29] argued that true vertigo occurring together with migraine is rare; "dizziness" is often mistaken for vertigo, but these entities differ clinically and biologically as vertigo is a hallmark of inner ear disease.
I was nervous talking about it because people already know I have an inner ear disease and a bad neck, and I was wondering if I wanted to come out with one more medical issue.
The induction of IL1R2 by IL-4 [32] certainly suggests that the maintenance of a TH2-like phenotype is important in controlling inner ear disease, whereas expression of IFNγ, that fosters a TH1-like response, has been observed in AIED patients [22], and blocks the expression of IL1R2 [33].
