Sentence examples for innate toxicity from inspiring English sources

In most cases, the toxic kidney lesions develop from innate toxicity of these medications, but underlying host risk factors and the renal handling of these drugs clearly increase the likelihood of nephrotoxicity [ 18, 30].

Experts speculated the reaction was more of an allergic one specific to the consumer, or a misidentification, rather than innate toxicity of the fungus, due to the wide range in effects seen.

These drug groups have a high innate toxicity, with both diuretics and oral anticoagulants requiring close monitoring for safe use.

Our studies suggest that ROS and UPS perturbations act upon the innate toxicity of disease-linked pathogenic proteins by observing degeneration in C. elegans neurons and a deleterious increase of phenotypic readouts in bodywall muscle cells expressing misfolded proteins.

Hence, in congruence with above facts and findings, this research aims to study the effect of surface altered ZnO NPs by TritonX-100 on preferential cytotoxicity in cancer cell invitro by comparing with innate preferential toxicity shown by unaltered ZnO NPs.

In addition to the concentration of particulate matter (PM), these effects have been related to innate particle toxicity.

There was no evidence of toxicity, and innate immunostimulation was not detectable following the injections.

Shortening these RNAs enables Integrated DNA Technologies to manufacture the components as high-quality, synthetic RNA oligonucleotides that elicit less toxicity and innate immune response activation in cells.

B cell deficient mice that maintain an otherwise intact innate response often show toxicity around 9 or 10 days post infection because of the lack of endogenous circulating antibodies and the production of neutralizing antibodies primarily against the N and G proteins by plasma cells.

To be useful in biomedical applications, the constructed nanospheres must have low toxicity and little innate bio-reactivity.

Furthermore, the dual peptides-modified liposomes showed superiority in anti-tumor efficacy, combination of anti-angiogenesis by VEGF siRNA and apoptosis effects by DTX, after both intratumor and system application against mice with U87 MG tumors, and the treatment did not activate system-associated toxicity or the innate immune response.