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We next performed chromatin immunoprecipitation assays, allowing for the analysis of transcription factors binding to their cognate sequences in an innate context of the promoter.
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By contrast, T cells, which are the key cells expressing type-II cytokines in allergy, are not the major IL-4 producers in this innate immune context.
In this context, innate immune priming of DC had differential effects on T cell polarization.
In the innate immune system context, epigenetic studies strongly implicate HAc in the transcriptional response of activated macrophages.
The problem with using this sense of "innate" in the context of distinguishing between "innate immunity" and "adaptive immunity" is that almost every aspect of the adaptive immune response, except for the final products of the immunoglobulin (Ig) and T cell receptor (TCR) gene rearrangements, are similarly determined (at least in large part) by information inherited through the germline.
We fall prey to what the social psychologist Lee Ross called "the fundamental attribution error" — the tendency to ascribe success or failure to innate characteristics, even when context is overwhelmingly important.
Examining results from functional neuroimaging studies on recovery in the context of innate hemispheric abilities may enable reconciliation of disparate claims about mechanisms supporting recovery from aphasia.
NOD1 and NOD2 are important members of the pattern recognition receptor family and play a crucial role within the context of innate immunity.
Absent the ability to show facial expressions or accompanying body language or context, any innate sense of self-editing -- "How will what I'm about to say affect this person and/or our relationship?" is gone.
This CD4 T cell phenotype may identify the cells, which are activated by chronic antigen stimulation in the context of innate immune system activation by microbial components.
In humans, little is known about the role of these or other cytokines in the context of innate or acquired anti-fungal defense mechanisms and only scarce data is available to validate the clinical and experimental findings so far.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com