Sentence examples for innate challenges from inspiring English sources

Such is the dynamic that has empowered creativity and flexibility in Dallas, as one of the league's top defensive outfits has created a culture of healthy experimentation in response to the innate challenges of preventing highly skilled athletes from doing what they do best.

He lost the visual debate with Biden not just because Biden hogged the lens, but also because of innate challenges the younger man faces as a television performer.

This study highlights the innate challenges in discovering statistical epistasis.

As discussed, there are many factors at the national level, from legislation to the policies derived from it, that create innate challenges for NHS/university partnerships.

Other authors have acknowledged the innate challenges in measuring customized WHP programs [ 58], and in this setting although the study's design did not capture specific details of availability or participation, it was able to deal with the heterogeneity of comprehensive WHP.

This complex is the key mediator of NF-κB activation in response to proinflammatory and innate immune challenges (Rothwarf et al, 1998).

Most importantly, the maternal LPS challenge caused corticosterone-independent blunting of the serum proinflammatory cytokine response to innate immune challenge in both male and female offspring.

We report that MPSI changes blastocyst cellular organisation and induces a complex postnatal phenotype affecting adult behaviour, adiposity and response to an innate immune challenge in a gender-specific manner that is dependent upon the originating maternal LPS dose.

Foxp3+IL-17+ T cells arise from the Foxp3+ROR-γt+ Treg subset and not the Foxp3+ROR-γt− population, indicating that the Foxp3+ROR-γt+ population possesses the ability to produce IL-17 under certain conditions of innate immune challenge.

We found that the maternal LPS challenge induces a typical and transient sickness response and, critically, altered developmental programming with abnormal blastocyst cell lineage allocation and led to postnatal changes in behaviour, adiposity and, following innate immune challenge, in cytokine release.

Offspring response to an innate immune challenge was assessed by measuring serum cytokine concentrations in LPS-injected (50 μg/kg) adult offspring of dams that were injected with saline or 10, 50 or 150 μg/kg LPS at the zygote stage.