Sentence examples for innate bone from inspiring English sources

This hierarchical signaling network model provides a conceptual framework for understanding innate bone repair and regeneration mechanisms and rationally designing regenerative therapeutics.

Microarray analysis of additional non-OA control samples could help to exclude differentially expressed genes driven by innate bone structure.

Another limitation was the difficulty distinguishing whether differentially expressed genes reflected OA progression in cartilage, differences in innate bone structure, or were driven by changes in mechanical loading.

While natural bone repair provides a unique precedent for stem cell-mediated tissue regeneration, enhancement of bone's innate regenerative capacity is necessary in order to meet the clinical needs of an aging population.

Tissue engineering seeks to harness the regenerative capacity innate to bone for the replacement of tissue lost or damaged through a broad range of conditions associated with an increasingly aged population.

To further analyze the role of p47phox during innate immunity, bone marrow-derived macrophages were stimulated with LPS and nuclear factor- κB activation was assessed.

They represent mechanisms involved in the innate response and bone remodelling processes.

The vitamin D endocrine system regulates a broad spectrum of independent biological processes including innate immune responses, bone metabolism, and cell proliferation and differentiation [ 23].

In particular, radiation induces apoptosis in mature T and B lymphocytes responsible for mediating adaptive immunity, causing lethal damage to the precursors of monocytes and granulocytes involved in innate immunity in bone marrow stem cells [ 35, 36].

TRAF6 has been proved as a key adapter in regulating various signaling pathways of inflammatory response and a diverse array of physiological processes, including adaptive immunity, innate immunity and bone metabolism, as well as development of several tissues including lymph nodes, mammary glands, skin and central nervous system [ 17, 18].

Bone has innate ability to regenerate following injury.