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Another function is in regeneration, as shown in H. echinata, where Möhrlen et al. [ 38] found astacins hea1 and hea2 expressed throughout development and soon after the gastrozooid is subjected to tissue injury (expression in other polyp types not mentioned).
In order to observe some of the cellular events, more specific migration of leucocytes at the site of injury, expression of the marker CD45 was analysed (Figure 8 a-f).
In the process of chick retinal pigmented epithelial (RPE) cell dedifferentiation and transdifferentiation after retinal injury, expression of these three pluripotent genes are also upregulated in injured RPE during short time comparing with non-injured one.
Thus, during the first phases of response to injury, expression of HO-1 was weaker in diabetic than in wild type animals.
In support of our proposed role of unphosphorylated and phosphorylated C/EBPβ-Thr217 on the modulation of HSC survival following their activation by liver injury, expression of the dominant positive phosphorylation mimic C/EBPβ-Glu217 [5] enhances survival of cultured progenitor neuronal cells [35] while C/EBPβ−/− macrophages display defective bacterial killing and tumor cytotoxicity [36].
The severity of lung injury, expression of VEGF and its receptors were assessed.
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We have also evaluated the post-injury expression profile of Nfh in the G93A-SOD1 tratsgenic rand and in their wild type (WT) littermates, together with the determination of spare white matter, of macrophage infiltration, of microglial activation and of the number and size of motor cells in the spinal cord segment immediately caudal to the site of injury.
During injury, hepatocyte expression of D1 decreased, whereas stromal expression of D3 increased, particularly in myofibroblasts.
It has been suggested that PAX3 activates genes associated with myogenic regulatory factors and after muscle injury, PAX3 expression increases within cells that express myogenic regulatory factors [ 53].
To clarify the effects of endogenous Homer1a on NMDA injury, Homer1a expression was significantly downregulated in LV-expressed Homer1a targeting shRNA group (RNAi-H1a; 1.50±0.17) when compared with the NT group (6.43±0.56-fold; Figures 3b and c).
Similar to results obtained by our puncture assay, the uromodulin-like gene was expressed in the aboral domain immediately after injury and expression appeared expanded at four hours after injury.
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