Sentence examples for injurious role from inspiring English sources
There is a growing concern of the potential injurious role of ventilatory over-distention in patients without lung injury.
Whether IL-6 plays a protective or injurious role on liver may depend on the duration of exposure to stress [30].
In addition, oxidative stress has been shown to have an injurious role in BRB integrity by disruption of tight junctions in retina [60].
Our data) support the potentially injurious role of IL-1β.
Consistent with the injurious role of IL-1, administration of IL-1β in rats results in increased brain damage (Yamasaki et al., 1995).
Myocardial GSK3β on the other hand plays an injurious role, active (de-phosphorylated) GSK-3β contributing to mitochondrial dysfunction and cell death (Juhaszova et al., 2009), with studies uniformly reporting cardiac protection via GSK3β inhibition.
The injurious roles of TNF-α, TLR4, and NF-κB in O3-induced lung pathogenesis have been determined in mice.
Although their metabolite products have been the subject of intense investigation due to their life-saving roles as medicinals and injurious roles as mycotoxins and virulence factors, little is known of the phylogenetic relationships of the corresponding NRPSs or whether they can be ranked into subgroups of common function.
The purpose of this study was to examine the role of injurious MV strategy in PARP activation and the effects of a PARP inhibitor, in the mouse VILI model of normal lung, under the hypothesis that PARP overactivation may participate in inflammatory and transcriptional mechanisms of VILI.
Additionally, pharmacologic inhibition of Tpl2 is effective in ameliorating indices of VILI, even when given after establishing injurious ventilation, suggesting a potential therapeutic role for Tpl2 inhibitors in VILI.
The mitochondrial binding of HKII has been shown to play an important role in cellular response to injurious agents (Majewski et al, 2004; Pastorino et al, 2002; Sun et al, 2008), production of ROS (da-Silva et al, 2004; Sun et al, 2008) and energy production (Pastorino & Hoek, 2003).
