Sentence examples for injurious pathways from inspiring English sources

The cascade of injurious pathways is initiated within minutes of the cessation of oxygen supply.

Many of the injurious pathways are executed over hours to days following return of spon¬taneous circulation (ROSC) [ 20],[ 21].

In summary, a body of evidence indicates that VDR and its agonists are capable of eliciting renoprotective effects through enhancing/maintaining nephrin expression and inhibiting injurious pathways to podocytes.

The contradicting results between the two models could be explained by the fact that the two models induce different types of liver injury and BALB/c mice may be susceptible to one injurious pathway but protected from another.

In the previous issue of Critical Care, Vaschetto and colleagues reported the results of an experimental study designed to further explore pathways linking injurious ventilation with AKI.

Moreover, inhibitors of ERK1/2 and PI3K prevent the damaging effects of HG on cultured VSMCs, suggesting that HG exerts injurious effects via these signaling pathways.

As this has not been reported for either of the single HPS mutant animals from which the HPS double mutant strain was derived, it appears that the combination of two vesicle trafficking disorders affecting separate pathways is especially injurious to long-term maintenance of lung homeostasis.

These findings suggest that METH preconditioning protects against striatal DA depletion, in part, by suppressing injurious mechanisms while also augmenting neuroprotective pathways in the nigrostriatal dopaminergic pathway.

It appears that the net effect of HCA on nitrogen radicals may be beneficial, perhaps because the oxidant pathway is more injurious.

Accumulating evidence points to GSK3β as a point of convergence for a number of nephropathic pathways downstream diverse renal injurious signals.

p21WAF1/Cip1 can be up-regulated as a consequence of cell cycle regulation, replicative senescence (associated with telomere shortening) or as a result of oxidative stress and other cell damage (e.g. p53 mediated) pathways 22. Acute injurious stimuli can, therefore, lead to senescence in the biliary epithelium, which causes an up-regulation in p21WAF1/Cip1.