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Among the leading causes of injury, poison as a form of injurious agent stands 2nd with falls being the first and burns, drowning following on.
All chronic injuries to the liver, whether viral, immune, metabolic, obstructive or toxic, lead to fibrosis regardless of the injurious agent or the route of injury [ 65].
They are the expression of a protective tissue response to injuries, which serves to destroy, dilute, or wall off both the injurious agent and the injured tissues.
Inflammation is a protective tissue response to injury or pathogens that serve to destroy, dilute, and/or wall off both the injurious agent and the injured tissue (Sparks 1985).
A mildly injurious agent that is present for short periods of time may either have little effect or stimulate cells to increased activity.
Its purpose is to localize and eliminate the injurious agent and to remove damaged tissue components so that the body can begin to heal.
Similar(41)
Normal vascular endothelium has anti-inflammatory properties, but endothelial function is impaired in the presence of inflammatory conditions and increased oxidative stress., When injurious agents persist or healing is disturbed, inflammation, tissue injury and attempts at repair coexist.
Strongly injurious agents in prolonged contact with cells cause characteristic changes in them by interfering with normal cell processes.
When stimulated, these receptors constrict the airways and cause rapid shallow breathing, which inhibits the penetration of injurious agents into the bronchial tree.
A clearer comprehension also emerged of the ways in which the cells of the body defend themselves by modifying their chemical activities to produce antibodies against injurious agents.
The severity of the changes that occur in cells and tissues subjected to injurious agents is dependent upon both the sensitivity of the tissue concerned and the nature and time course of the agent.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com