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Hepatic ischemia reperfusion (I/R) injury mainly occurs following hepatic resection and liver transplantation and cause severe liver damage, organ injuries, and dysfunction.
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Myocardial injury and dysfunction are critical manifestations of sepsis.
"There is evidence of brain injury and dysfunction," Zada said.
The vascular endothelial cell injury and dysfunction prolong ischemia and induce vascular congestion, edema, and further infiltration of inflammatory cells.
Treatment of endothelial cells with these lipoproteins stimulates monocyte binding and the production of chemotactic factors that contribute to inflammation and endothelial injury and dysfunction.
Meanwhile, T0901317 treatment improved mice survival, accompanied by significant ameliorations of myocardial injury and dysfunction in wild-type mice but not in SIRT1-/ mice.
Therefore, we conclude that alternative use of isoflurane and propofol confers superior cardioprotection against postischemic myocardial injury and dysfunction, and this protection was probably mediated by attenuation of cardiac oxidative damage.
Circulating numbers of endothelial microparticles (EMP) are an index of endothelial injury and dysfunction; and microparticles positive to CD31 antibody increase acutely after cooked, fatty fast-food meals that are rich in saturated fatty acids (SAFA) and lipid oxidation products.
Taken together, all these changes can ultimately lead to cellular and tissue injury and dysfunction [31].
In a sheep model of renal I-R, BH4 pre-treatment can prevent microvascular injury and dysfunction.
Despite the term ATN, actual necrosis of tubular epithelium cells is a less common finding than cellular injury and dysfunction.
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