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The competing antibody was then injected and the change in sensorgram signal was recorded until subsequent injections achieved saturation.
Some patients initially progressed but, continuing IL-12 injections, achieved minor or even partial responses.
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Water injection, achieved when transforming the mGT into a micro Humid Air Turbine (mHAT), allows making use of the exhaust gas heat in such cases, thus increasing electrical efficiency of the technology and improving its feasibility.
In the STRIVE placebo-controlled Phase 3 trial in patients with episodic migraine (EM; clinicaltrials.gov NCT02456740), erenumab 70 mg and 140 mg administered monthly by subcutaneous injection achieved the primary endpoint of significantly reducing the number of monthly migraine days versus placebo.
Approximately 40% of patients who received lixisenatide morning or evening injection achieved an HbA1c <7.0% (<53 mmol/mol) compared with ∼20% of those who received placebo.
NRG1 injection achieved comparable beneficial effects as MSCe, but MSC-ERBB4 substantially outperformed NRG1 and MSCe, exhibiting a much smaller fibrotic area, and more effectively preserved LV wall thickness.
In the case of multiple injections we assume that the doses are such that the plasma concentration regains its initial value at each injection (achieved mathematically in (6) by making the time variable modulo T per ).
Although the injection achieved a sustained therapeutic concentration, no beneficial effect of IM betamethasone on postoperative pain or reduction in pain relief drugs was observed during the postoperative period.
Mud grouts incorporating the original soil of the rammed earth are shown to perform better and their injection achieves satisfactory shear strength recovery, but is less effective in recovering initial shear stiffness.
Cyclic CO2 injection achieves an incremental 2.4% recovery factor (over four years of operation) with high energy return ratio whereas CO2-hot water processes achieve higher recovery factors with lower energy return ratios.
Icatibant is administered subcutaneously as a single 30-mg injection, achieving peak concentration within 30 min, and has a half-life of 1 2 h.
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