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The resulting P-values were P < 0.001 for both comparisons: post PTZ injection slope to the baseline slope and post PTZ injection slope to the post saline injection slope.
The average baseline slope was −0.16 x 10−3 NI/t and the average post saline injection slope was −0.59 x 10−3 NI/t.
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This procedure also compared the post PTZ injection slopes to the baseline and post saline injection slopes.
To quantify our results, we calculated the baseline and post saline injection slopes through linear regression of the data in Fig. 2B for all four experiments.
The intervals, from which the baseline slopes were calculated, began at time zero and ended at saline injection and the post saline injection slopes were calculated from the administration of the saline injection to PTZ injection.
We used a Tukey multiple comparisons test to compare baseline, post saline injection, and post PTZ injection slopes and our results indicated no significant change in intensity between baseline and post saline inj.
We then averaged the four slopes and plotted them in Fig. 4 along with the baseline and post saline injection average slopes.
However, limited data are available on its relationship with invasive assessment by phenylephrine injection (Phe-slope).
In the aortic arch at 30 min after injection, the correlation coefficient, slope, and intercept was 0.98, 1.15, and -372, respectively.
In the three patients given boost injection(s), the log slope PSA decreased further indicating that biochemical response comes late and that such patients may need to be boosted for a longer time period.
Similarly, there were effects of injection condition on the slope (F2,8 = 13.5; P < 0.003) and amplitude (F2,8 = 10.3; P = 0.006), which were lower in the contralateral condition compared with both baseline (slope: P = 0.01; amplitude: P = 0.02) and ipsilateral (slope: P = 0.02; amplitude: P = 0.04) conditions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com