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The CLA-coupled poloxamer designed in this study has great potential as an effective injectable carrier of PTX.
Gelatin and Laponite® were combined to formulate a shear-thinning, nanocomposite hydrogel (nSi Gel) as an injectable carrier of secretome (nSi Gel+).
As it was mentioned in a review published by Mikos et al., due to the advantages of injectable materials for both drug delivery systems and tissue engineering, the experience transfer from injectable carrier in field of DDS in order to reach appropriate in situ forming scaffolds is warranted (Jia and Kiick 2009).
This work describes the development of heparinized polymeric micelle as a novel injectable carrier for the dual drug delivery that can simultaneously release basic fibroblast growth factor (bFGF) and indomethacin (IMC), which can promote the regeneration of damaged tissue and prevent the inflammatory response after implantation.
The results suggest that the self cross-linkable thermosensitive polyphosphazene blend systems have great potentials to play a crucial role as an injectable carrier because of their improved suitable mechanical properties for application potentials, in addition to their inherent advantages such as injectable, biodegradable and thermosensitive properties.
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We designed injectable carriers for cell delivery derived from reactive, hydrophobic polyisocyanate and polyester triol precursors.
Development of biodegradable thermogels as intracameral injectable carriers for ocular delivery of antiglaucoma medications can provide a better treatment modality with low dosing frequency than eye drop formulations.
Currently, one of the most widely used injectable carriers is hydrogel due to its unique characteristics including the ability to fit defective cavities of any shape and size, quick gelation and construction for uniform distribution of transplanted cells, and high water content to mimic native tissue (Wang et al., 2010).
In this study, a hydrogel scaffold of poly(NiPAAm-co-AAc) was utilized as an injectable delivery carrier containing cell and growth factors for engineering of cartilage tissue.
These results suggest that temporary encapsulation of cells in gelatin microparticles may protect cells from short-term environmental effects such as those associated with the crosslinking of an injectable polymeric carrier for bone tissue engineering.
The aim of this work is to synthesize such a material as a conformal coating on a nanoparticle as an injectable drug carrier with release activated by exposure to NIR light.
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