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The inverse relationship between 5' secondary structure and sensitivity to inhibition by a dominant-negative mutant of eIF4A [11] is consistent with the idea that eIF4A functions to unwind secondary structure in the 5' UTR during initiation to create a ribosome landing pad.
Providers will be included in the orientation at the time of study initiation to create a general on-site understanding of the study.
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Since none of the stop codons (TGA, TAG, and TAA) ends in AT, GT, or TT (needed to create the initiation codons ATG, GTG or TTG in phase-1 two-nucleotide overlap) or start with G (needed to create an initiation codon in phase-1 five-nucleotide overlap), short phase-1 overlaps can only use alternative initiation codons.
European Union (EU) regional policy came about in the early 1970s with the initiation of the legislative process to create the Regional Development Fund (CEC 1973).
The T. brucei MURF2 mRNA is edited at the 5' end by the insertion of 24 uridine residues to create the initiation codon and the reading frame up to nt 45 of the ORF.
iCVD works by selectively fragmenting gaseous TBPO with heat to create radicals for initiation of polymerization.
Thus, it seems indeed rather conceivable that random mutations in such potentially active regions might suffice to create a new regulated initiation site.
Our analysis revealed that lateral root initiation and lateral root development/emergence are interacting with each other to create a global balance between the respective ratio of initiation and emergence.
Such information is required to create strategies to prevent the initiation or progression of aberrant epigenetic silencing.
Centralized HIV care at the hospital level tends to create additional bottlenecks in treatment initiation, and creates difficulties with transport and time off work for the patients [ 29, 35, 36].
Responses were collapsed to create two binary variables assessing initiation of use and frequency of use.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com