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We show that the set of initiating autoantibodies is usually limited to Ro, nRNP A, phospholipids and rheumatoid factor of the specificities tested, suggesting that there appears to be an autoantigentic bottleneck that restricts autoantibody initiation to a relatively small number of initial antigenic structures on the pathway to SLE development.
Dr. Norbert Sander, who has helped turn the armory in Manhattan into something of an international mecca, remembers his initiation to a flat wooden track, 11 laps to the mile.
Originally born Chad Ferguson, Joe's initiation to a life of petty thievery and chasing highs started on his 18th birthday when he robbed a Domino's Pizza.
In this population time since HIV diagnosis closely coincides with time since ART initiation to a large extent making up for the missing values on time on ART.
As replication timing maps are population averages, assigning an initiation to a particular time (the midpoint of the probability distribution of initiations for that origin) is an approximation.
Similarly, the activity of Apaf-1 IRES is dependent on the binding of two RNA binding proteins, PTB and unr, that change the structure of Apaf-1 IRES such that it permits ribosome landing (and consequent translation initiation) to a single stranded region [14].
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The transition from an initiation to an elongation complex is accompanied by a major refolding of the amino-terminal 300 residues.
Generally, the catalytic action of the HCV-polymerase involves a conformational transition from an initiation to an elongation state.
Hypothesis: The parents' turns would shift from a predominance of initiations to a predominance of responses as a result of attendance on the course.
She along with the Dauntless initiates from other factions must make it through initiation to become a member of the Dauntless.
This initiation to conking — a back-seat deflowering, of sorts — persuaded Malcolm that if black people "gave the brains in their heads just half as much attention as they do their hair, they would be a thousand times better off".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com