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This climate hampered the uptake of insulin initiation therapy among GPs.
When CUP is diagnosed in the peritoneum or pelvis., even in the primary site cannot be identified, the initiation therapy targeting ovarian cancer could be considered [ 2].
Therefore, basal insulin as a first-line insulin initiation therapy is now recommended in a joint consensus guideline by the ADA and EASD (11).
Recent mounting evidence indicates that cancer stem cells (CSCs) play a crucial role in tumor initiation, therapy resistance, disease relapse, and tumor progression [ 5– 7].
Likewise, the CSC hypothesis similarly predicts that a subset of self-renewing cancer cells is responsible for tumor initiation, therapy resistance, delayed cancer recurrence and metastatic progression.
Following malignant transformation, so termed cancer stem cells (CSC), endowed with the same properties as SSC (i.e. the ability to both self-renew and generate differentiated progenitors), play a major part in tumor initiation, therapy resistance and ultimately relapse.
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CTC counts were performed at baseline, before the initiation of therapy, and throughout therapy.
"In some, but not all patients, options for the preservation of fertility can be explored before the initiation of therapy".
However, he developed paradoxical worsening 2 months after initiation of therapy.
Twelve months after the initiation of therapy, the patient remains asymptomatic (Fig. 2).
T indicates the initiation of therapy (systemic methotrexate and/or rituximab).
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CEO of Professional Science Editing for Scientists @ prosciediting.com