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By the approach taken here, transcriptional initiation outside of the LTR cannot be distinguished from LTR-initiated transcription.
As for Professor Aronson, had he not wanted tight control over the experiment, he writes in his widely used textbook, "The Social Animal," he and Professor Mills could simply have studied an initiation outside the lab -- at a campus fraternity or sorority.
The findings of the literature analysis are insufficient to enable a recommendation concerning the optimal timing of RRT initiation, outside life-threatening situations.
Cases with transcription initiation outside the locus are more difficult to interpret.
Some coinfected individuals are, therefore, likely to have died prior to initiation, outside of Mpilo hospital and the association between TB and LTFU may reflect additional unrecorded deaths.
Both overlap distinct peaks of RNAPII binding, suggesting that their biogenesis is tied to RNAPII molecules heading in opposite directions, possibly linked to nucleosome position [ 4], and this reinforces our previous finding that tiRNAs are found at sites of active RNAPII transcription initiation outside of canonical transcription start sites.
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Other reasons for exclusion were the mistaken inclusion of patients commencing RRT for ESRD (n = 3); RRT initiation at an outside facility (n = 3); the receipt of isolated ultrafiltration as the initial RRT modality (n = 3); or missing information on initial modality or outcome (n = 8) (Fig. 1).
The use of initiation sites outside oriP differs between different strains [28] and is consistent with the observation that also ORC-binding is not limited to oriP [29].
Since yet another TSP signal could be recognized further upstream of TSP3 in some primer extension analyses using C. glutamicum (pET2 sigH), the 348-bp upstream fragment (462 to 115 nt upstream of the sigH initiation codon, outside of P1, P2 and P3) was separately cloned in pET2 (resulting in pET2 sigH4).
Their C-terminal domain binds to cell surface receptors and is thereby responsible for cell anchorage and the initiation of specific outside-in and inside-out signals.
After leakage initiation, fluorescence intensity outside of the vessel increased to its maximum, signifying closure of the leakage points.
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