Sentence examples for initiation of the er from inspiring English sources

In summary, this study reveals a novel role for CN at the initiation of the ER stress cascade.

After initiation of the ER program, the mortality rate following primary hip and knee arthroplasty was reduced (p = 0.05) at 2 years (Table 2).

Increased GRP78 expression was observed in ACC-M and ACC-2 cells upon exogenous C2-ceramide treatment, indicating initiation of the ER stress and activation of the UPR cascades.

In Wolfram syndrome, WFS1 mutations lead to elevated ER stress levels, pancreatic β cell dysfunction, and the initiation of ER stress-associated cell death [ 28, 30].

20 Accordingly, the FDA has developed guidelines to ensure that women of childbearing potential are informed of the possible teratogenic risks of the treatment, recommending that pregnancy testing be conducted prior to initiation of phentermine/topiramate ER, and suggesting that monthly pregnancy testing be performed thereafter.

We found that AATF mRNA expression continued to increase up to 24 hr after the initiation of ER stress.

Perturbation of the ER can lead to a phenomenon termed ER stress which results in the initiation of signalling networks aimed at restoration of ER equilibrium.

According to the model, the limit to the folding capacity of the ER is a major determinant of the initiation of apoptosis.

It has been reported that deletion of Wfs1 results in ER stress and the initiation of the UPR (Fonseca et al, 2010; Yamada, 2006).

When misfolded proteins are accumulating in the ER lumen, BiP dissociates from the stress transducers in order to chaperone the misfolded proteins, which leads to an activation of ER stress transducers and an initiation of the UPR [ 9, 11].

These results suggest that the initiation of the response to salinomycin does not depend on Ca2+ stored in the ER.