Sentence examples for initiation of the differentiation from inspiring English sources

A plausible explanation would be that shortly after initiation of the differentiation process, genes that arrange the differentiating cell towards its new function are up-regulated.

γ-Irradiation after an initial proliferation phase induced by CD40 ligand and immediately prior to initiation of the differentiation phase blocked cell growth but did not affect cell viability or plasma cell differentiation.

We collected C2C12 cells at different growth states 24, 48, and 72 h after initiation of the differentiation stimulus.

While promoting abnormal differentiation, TSA specifically represses transcription initiation of the differentiation marker profilaggrin.

Upon initiation of the differentiation process, mitochondria in MSCs are activated via a yet unknown mechanism and oxidative phosphorylation becomes the major source of ATP.

The resulting data revealed that besides the expression of nestin (69.39%±12.25), subpopulations of the cells already express β-III-tubulin (21.8%±3.3), GFAP (9.33%±3.72), and α-SMA (29.72%±8.26) before the initiation of the differentiation.

STAT6 is not only implicated in the initiation of Th2 differentiation, but it also contributes to maintenance of the Th2 phenotype by inducing the expression of chemokines and other Th2-relevant genes 20, 28– 31.

The fact that Th2 cells themselves are the most potent source of IL-4 suggests that additional mechanisms promoting the initiation of Th2 differentiation exist.

Three days after the initiation of the cells differentiation, the differentiation media were replaced with adipocyte nutrition medium containing 3% FCS, d-biotin 8 ug/ml, 0.5 ug/ml bovine insulin and 400 ng/ml dexamethasone for a period of 16 days (terminal phase of differentiation).

The expression of lineage markers before the initiation of the neuronal differentiation underlines the spontaneous differentiation of pSSCs during expansion; maybe induced by the fetal calf serum and due to the primary neurogenic conditions (bFGF, EGF, and B27) of the stem cell medium (SCM).

These results suggest that histamine does not induce the degradation of preformed differentiation-associated proteins, but it rather blocks the initiation of the late differentiation program in keratinocytes.