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It is therefore necessary to focus prevention strategies on avoiding starting drug injection, sharing of injection paraphernalia and own reuse, and initiation of injection for both the initiator and the initiated.
Mice were sacrificed by cervical dislocation at three time points: four, eight, and 12 weeks after initiation of injection.
The delay between the initiation of injection and evaluation of contrast enhancement was 60 s for early-phase imaging and 90 s for late-phase imaging.
Shorter duration of symptoms before the initiation of injection therapy appears to be a positive predictor of outcome of treatment (Kaplan et al. 1990).
The median age for initiation of injection drug use was 17.5 years [IQR = 15-23], and the median age of crack cocaine use was 20 years [IQR = 16-29.8].
Studies that have explored HCV prevalence and incidence as a function of time since initiation of injection have found incidence rates in excess of 20% per year beginning in the first few years after initiation [ 33, 35, 42- 44].
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Mice were given two weekly intraperitoneal injections of 10 mg/kg of AOM and sacrificed at 6 weeks following initiation of AOM injection (supplementary fig 1B).
The portal venous phase was obtained 70 s after the initiation of intravenous injection of contrast agent.
The emission scan started upon the initiation of the injection, and dynamic emission data were acquired for a total of 240 min.
Finally, the pressor effects of IV cocaine paralleled the rapidly peaking arterial plasma levels of cocaine noted within 30 s after the initiation of drug injection.
The most significant changes of σ' occurred at the beginning of the column experiment and the initiation of urea injection due to the significant changes in TDS associated with salt dissolution and/or ion desorption and urea hydrolysis, respectively.
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