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To explore socio-demographic factors, health risks and harms associated with early initiation of injecting (before age 16) among injecting drug users (IDUs) in Tallinn, Estonia.
Similarly, there were no differences in age of initiation of injecting drug use, drug dependence, or injecting risk behaviours.
However this does not allow for the delay from the initiation of injecting until coming into contact with services.
HCV infection is rapidly acquired after initiation of injecting and incidence rates are highest among newer injectors, a quarter of whom are infected within 2 years of initiating.
The best fitting multinomial logistic model included duration variables of 1 year, 2-10 years, 11-15 years, and 16-38 years from initiation of injecting and the opiate substitution treatment and age at onset of injecting variables as continuous variables.
Female participants with follow-up were younger than male participants with follow-up (median 21 vs 23 years, p<0.01) at the time of enrolment and reported younger age of initiation of injecting (median 17 vs 19 years, p<0.01; table 1).
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Our modelling attempted to account for sexually transmitted HIV among PWID by allowing a proportion of PWID to be already HIV infected at their initiation to injecting (8%), and by assuming a continued rate of sexual HIV transmission among PWID.
Scotland was quick to invest in blood-borne virus prevalence studies (11– 13) and in capture-recapture estimation of its current IDUs (14, 15), but incidence studies whether of blood-borne viruses (16) or initiations to injecting (3)—were initially lacking.
To verify if EcR-USP was responsible for 20E action in regulating innate immunity in Bombyx fat body, larvae at the initiation of EW were injected with EcR and/or USP dsRNA and then a series of assays were performed at 24 hours after RNAi treatment.
Large-scale IDU incidence studies to quantify the rate of initiations to injecting have been few, as these are hard to design well.
Mass of injected fuel.
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