Sentence examples for initiation of gene expression from inspiring English sources

Gene regulatory networks have both transcriptional and epigenetic components, including regulation of the initiation of gene expression through the action of transcription factors, the pre-transcriptional epigenetic regulation through promoter methylation, and the post-transcriptional regulation of mRNA stability or translation through the action of microRNAs (Fig.  3).

At 24 h after initiation of gene expression, the OPLlTE expression level and fatty acid production in SGJS47 increased up to 15.8-fold and 3.2-fold compared to the control and other recombinant strains, respectively.

pp72-IE1 is expressed with immediate early kinetics upon infection and is not part of the HCMV particle and therefore constitutes a marker for successful HCMV entry and initiation of gene expression.

Therefore, a suitable metabolic state achieved prior to germination may be necessary for the initiation of gene expression programs for efficient seedling development.

In particular, it has been shown that specific proteins bind to CpG islands to create chromatin environments that are more favourable for the initiation of gene expression.

Moleskin, for example, appears to be involved in EGF receptor signalling pathway initiation of gene expression in response to Drosophila receptor tyrosine kinase signalling [ 70].

A bias toward post-initiation regulation of gene expression may have been facilitated by the homeostatically controlled environments within human and insect hosts, thereby relieving selective pressure for the retention of fine control at the level of transcription initiation.

The R region is important for both transcription initiation and regulation of gene expression in other retroviruses as well.

The complexes then translocate into the nucleus where they participate in the initiation or repression of gene expression, thereby regulating the transcription of target genes [ 11].

Finally, in mammals, XPC, XPA, XPF and XPG were found to be present at the promoters of active genes, and ERCC1, XPF and XPG were specifically implicated in the regulation of hepatic transcription initiation and regulation of gene expression, suggesting that a defect in transcription could contribute to observed phenotypes.

We would also advocate the initiation of microarray studies of gene expression in samples taken from subjects with ADHD.